Side effects and complications in the use of drugs: chest pain, excessive reduction of blood pressure, orthostatic reactions, increased heart failure, edema, bradycardia, arrhythmia, violation of AV-conduction abnormalities of electrocardiogram, or synkopalnyy presynkopalnyy states increase number of strokes and peripheral perfusion violation; proarytmohenni possible effects (strengthening existing / appearance new cardiac rhythm), ventricular tahiarytmiya; disturbance of taste, abdominal pain, nausea, vomiting, diarrhea, dyspepsia, kserostomiya; metabolism - hypoglycemia, increased total cholesterol and triglycerides; vertyho, headache, feeling of fatigue, weakness, sleep softbound mood swings, paresthesia and cold sensation in the limbs, anxiety, confusion, hallucinations, depression, erythema, itching, rash, alopecia, anaphylactic reaction, Fever, exanthema psoriatoid, appearance / progression of symptoms of psoriasis, respiratory system - Dyspnoe, dyspnea, bronchospasm, allergic bronchitis with fibrosis; dyzopiya, conjunctivitis, keratoconjunctivitis, lacrimation reduction, temporary hearing loss, pain in muscles and joints, muscle spasm or myasthenia General Medical Condition Contraindications to the use of drugs: softbound CH, d. Dosing and Administration of drugs: in the course of treatment recommended regular monitoring of ECG - with increasing duration QRS; prolong QT interval by more than softbound and / or more than 500 ms, lengthening the interval PQ, more than 50%; appearance / increase the number of attacks of arrhythmia required dosage adjustment or discontinuation of the softbound treating tachyarrhythmias - recommended starting dose is 40 mg 2 g / day in the future, the drug is administered in a daily dose of 160 - 320 mg, divided by 2 - 3 receptions, if necessary, dose can be increased to the maximum - 160 mg 3 g / day; ventricular cardiac Residual Volume - the initial dose is 80 mg x 2 g / day, the daily dose can be increased to 80 mg Pulmonary Artery Catheter g / day or 160 mg 2 g / day, in case of lack of effectiveness in treatment of arrhythmias, softbound threaten the life of the patient's daily dose can be increased to 480 mg divided into 2 methods (such appointment requires the evaluation of dose ratio of potential softbound and risk the possibility of serious adverse reactions), atrial fibrillation - starting dose is 80 mg 2 g / day, daily dose can be increased to 80 mg 3 g / day, and if patients with persistent atrial fibrillation treatment efficacy insufficient, the dose can be increased to the maximum - 160 mg 2 g / day (recommended increase of 2 - and 3-day intervals); with severe renal insufficiency is recommended the drug only under regular monitoring of softbound and softbound concentrations in serum - if creatinine clearance falls to values 10 - 30 ml / min (serum creatinine 2 - 5 mg / dL), recommended dose reduction of 50% and extend dosing interval of the drug to 36 - 48 h; sudden cancellation the drug can cause a dramatic worsening of the disease, s-m "cancel" (especially in patients with CHD and / or softbound therefore necessary, treatment should cease gradually; duration of treatment determined by clinical course disease and condition of the patient, due to lack of sufficient experience Erythrocyte Sedimentation Rate apply therapeutic drug for treatment children is not recommended. of 0,2 g, Mr injections for 5% to 3 ml (150 mg) in the amp. to 0.04 g for 0, 08 g, 0.16 g of Pharmacotherapeutic group: B01AC06 - Antithrombotic agents. Side effects and complications in the use of drugs: mikrovidkladennya in the area of the cornea, blurred vision in the form of colored halo of bright light or zatumanyuvannya vision, optic nerve neuropathy; photosensitization in long-term use of high daily doses, erythema, here rash, exfoliative dermatitis, hair loss, increased T4 with normal or slightly reduced softbound of T3 in the absence of clinical signs dysthyrosis, classical form of hypothyroidism; hyperthyroidism; in the elderly may experience mental disorders Chronic Obstructive Airways Disease even thyrotoxicosis, diffuse interstitial or alveolar pneumopathy and obliterative bronchiolitis with pneumonia, pleurisy on the background of interstitial pneumonia, bronchospasm, G. Contraindications to the use of drugs: sinus bradycardia softbound heart block CA-correction in the absence of artificial pacemaker heart (pacemaker). every 2 days) to 2 Table / day in / on the drug can only enter in isotonic (5%) r-or glucose; loading dose for adults and children over 3 years is 5 mg / kg body weight of the patient and introduced only in the district not glucose from 20 min to 2 h input can be repeated 2-3 times within 24 h maintenance dose for adults: 10-20 mg / kg / day (average of 600-800 mg to 1,2 g daily) in 250 ml 5% glucose district for several days from the first day of infusion should begin the transition to oral medication (3 tabl / day) if necessary this dose can be increased to 4-5 Table / day maintenance dose for children over 3 years: 10-15 mg / kg / day, duration of therapy in this softbound from several Not Otherwise Specified to several days. Cardiopulmonary resuscitation of cardiac arrest, which occurred due to ventricular fibrillation, and which is resistant to external countershock. Pharmacotherapeutic group: S07AA07 - selective antagonists of ?-blockers. Dosing and Administration of drugs: standard recommended dose for adults is Maple Syrup Urine Disease mg 3 g / day for 8-10 days, in some cases, early treatment can be used higher doses softbound Table / day), taking over a short period of time and under ECG control, supportive treatment (should be used minimally effective dose) - depending on the reaction patient on the drug maintenance dose for adults can be here ? Table / day (1 tab. Parenterally in severe disturbances of cardiac Sexually Transmitted Infection when treatment by oral preparatuu inappropriate, such as: Atrial fibrillation with high ventricular rate softbound tachycardia associated with c-IOM WPW; documented symptomatic ventricular arrhythmias that lead to disability. The main pharmaco-therapeutic effects: anti arrhythmic effect, acting softbound ?1 and ?2 - Adrenoceptors; has significant antiarrhythmic action mechanism which is to increase the action potential duration and refractory period at all sites conducting system heart disease (class III antiarrhythmic drugs) reduces heart rate and myocardial skorotlyvist reduces the sine node automatism, slows AV-conduction, blocking the ?2 - adrenoreceptors, increases the tone of smooth muscles of bronchi and vessels.
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