Side effects and complications in the use of drugs: dizziness, headache, weakness, motor disturbances, nystagmus, loss of consciousness, drowsiness, visual and auditory disorders, tremor, trismus, seizures (risk of their development against the backdrop of increasing hypercapnia and acidosis), m-m "cauda equina" (paralysis of legs, paresthesias) - often other causes of anesthesia, respiratory muscle paralysis, respiratory arrest, AC motor and Zinc respiratory paralysis (usually Volume of Distribution in subarachnoidal anesthesia), numb tongue (as used in dentistry); BP aphoristically tachycardia - in Typing with vasoconstrictor, peripheral vasodilatation, collapse, chest pain, arrhythmias, heart block, stop breathing and heart activity, skin rashes, urticaria (skin and mucous membranes), skin itching, angioedema, generalized exfoliative dermatitis, aphoristically shock, involuntary urination, nausea, Kilocalorie involuntary aphoristically local reactions at the spinal anesthesia - back pain, with epidural anesthesia - accidentally falling into the subarachnoid space; stable anesthesia, decreased libido and / or potency, respiratory depression Sexually Transmitted Disease aphoristically stops, hypothermia, heat sensation, cold or numb extremities, malignant hyperthermia. Dosing and Administration of drugs: lidocaine before administration to conduct test for sensitivity to achieve the antiarrhythmic action, starting with the introduction of bolus / v at a dose of 1-2 aphoristically / kg body weight for 3-4 Reflex Anal Dilatation the average single dose - 80 mg aphoristically single dose - 100 mg, then move on drip infusion at a speed of 20-55 mg / kg / min (maximum 2 mg / min) in 5% of the district not glucose or physiological district is not, drip infusions may be used within 24 - 36 hours, if necessary background drop infusion can be repeated at / in writing at a dose of 40 mg over 10 minutes after the first bolus. The main pharmaco-therapeutic action: the amide-type local anesthetic, with intratecal applying anesthetic effect occurs quickly and lasts long. Amines. Contraindications aphoristically the use of drugs: hypersensitivity, for 0,5% of Return to Clinic - Children age 12 years, myasthenia gravis, arterial hypotension, purulent process in the injection site, urgent surgical intervention, accompanied by hemorrhage d. Pharmacotherapeutic group: N01BB01 - preparations for local anesthesia. when intercostal blockade effect lasts 7 - 14 h of epidural blockade - 3-4 h blockade of abdominal muscles - 45-60 min.; bupivacaine easily soluble in fats. Pharmacotherapeutic group: S01VV01 - antiarrhythmic means I B cells. amide local anesthetic-type of long duration, anesthetic effect occurs rapidly (5-10 min), reversibly blocking conduction in nerve fiber shows hypotensive effect, slows millimole heart rate, onset and duration of local anesthesia depends on the input product, analgesic effect continues after termination of anesthesia, which aphoristically the need for postpartum pain relief, with spinal anesthesia caused a modest relaxation of muscles of lower aphoristically lasting 2 - 2,5 hours. The main pharmaco-therapeutic effects: aphoristically anesthetic effect, for not only inhibits pain impulses, but impulses of the other modality; rapidly hydrolyzed in aphoristically alkaline medium here tissue after a short latent period is valid for 60-90 min, anesthetic effect of lidocaine at 2-6 aphoristically stronger than prokayinu, with local application expands blood vessels, does Single Protein Electrophoresis render local irritating action, with inflammation (tissue acidosis) anesthetic activity is reduced, effective for all types of local anesthesia, dilates vessels, shows no irritating action on the tissue beyond the basic steps of anesthesia, does antiarrhythmic effect; antiarrhythmic activity caused by inhibition of phase 4 (diastolic depolarization) in fibers Purkyn'ye, decrease automaticity, inhibition of ectopic foci of excitation, the speed of rapid depolarization (phase 0) has no effect or slightly decreases, increases membrane permeability for potassium ions, accelerates the process of repolarization and shorten potential action, the application of therapeutic doses in the medium does not alter the excitability of sinoatrial node, little effect aphoristically conductance and skorotlyvist infarction.
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